Have you ever heard of any correlation between barometric pressure and the onset of vertigo attacks? I have noticed that during days where the air is "heavy" I tend to have more symptoms. I also recently spent a vacation up in the mountains and I was miserable the whole time. I was at a high altitude and it was an extremely humid week in the summer.

Yes, I have heard many patients report that slow pressure changes can make symptoms worse, whether it is from driving up a mountain, the passing of a weather front or those occurring during flying. As yet there is no scientific explanation of this phenomenon. It could be that the ear with Meniere's cannot compensate for pressure changes as well as a normal ear in some way. However, since the inner ear is fluid-filled, and fluids are incompressible, there is no reason why atmospheric pressure changes should change the degree of endolymphatic hydrops (thought to be related to the symptoms). On the other hand, there are also other pressure-sensitive systems in the body involved in the maintenance of normal blood volume. These systems operate by releasing hormones which affect kidney function, which release or retain fluid thereby regulating the overall blood volume. It is possible that the ear is sensitive to either the blood electrolyte changes generated by the kidneys or directly to the hormone itself in some way that increases the liklihood of symptoms. In our current research projects, we are investigating how slow pressure changes affect the ear and how some of the fluid-balance hormones affect the ear. Maybe this work will lead to an explanation for your observations, and perhaps an appropriate treatment to relieve them. See also our survey of pressure effects on patients with Meniere's disease